abstract：AIMS:Chronic heart failure (CHF) is associated with a higher risk for diabetes mellitus. Retinol binding protein 4 (RBP 4) is an adipose tissue-derived protein with pro-diabetogenic effects. A complete understanding of the association of CHF and insulin resistance remains elusive. The purpose of this study was to exami...

journal_title：European journal of heart failure

authors： Bobbert P,Weithäuser A,Andres J,Bobbert T,Kühl U,Schultheiss HP,Rauch U,Skurk C

更新日期：2009-12-01 00:00:00

abstract：AIMS:Chronic hypertension may cause left ventricular hypertrophy (LVH). The role of matrix metalloproteinases (MMPs), tissue inhibitors of matrix metalloproteinases (TIMPs), and tenascin-C (Tn-C) splice variants in concentric vs. eccentric left ventricular remodelling has not been investigated. METHODS AND RESULTS:Ser...

journal_title：European journal of heart failure

authors： Franz M,Berndt A,Altendorf-Hofmann A,Fiedler N,Richter P,Schumm J,Fritzenwanger M,Figulla HR,Brehm BR

更新日期：2009-11-01 00:00:00

abstract：AIMS:To test the hypothesis that an earlier post-acute myocardial infarction (AMI) eplerenone initiation in patients with left ventricular systolic dysfunction (LVSD) and heart failure (HF) is associated with better long-term outcomes. METHODS AND RESULTS:The 6632 patients of the EPHESUS study were randomized from day...

journal_title：European journal of heart failure

authors： Adamopoulos C,Ahmed A,Fay R,Angioi M,Filippatos G,Vincent J,Pitt B,Zannad F,EPHESUS Investigators.

更新日期：2009-11-01 00:00:00

abstract：AIMS:To assess the prognostic value of a wide spectrum of neurohormonal and inflammatory markers along with functional status and exercise capacity, in hospitalized chronic heart failure (CHF) patients with depressive symptoms. METHODS AND RESULTS:A total of 300 consecutive hospitalized CHF patients were screened for ...

journal_title：European journal of heart failure

authors： Parissis JT,Farmakis D,Nikolaou M,Birmpa D,Bistola V,Paraskevaidis I,Ikonomidis I,Gaitani S,Venetsanou K,Filippatos G,Kremastinos DT

更新日期：2009-10-01 00:00:00

abstract：AIMS:Heart failure (HF) with normal or preserved left ventricular (LV) ejection fraction (HFPEF) has been reported to be associated with similar outcome as HF with reduced EF (HFREF) in registry-based and epidemiological analyses, but many of these studies excluded patients who did not have EF measurements. Conversely,...

journal_title：European journal of heart failure

authors： Somaratne JB,Berry C,McMurray JJ,Poppe KK,Doughty RN,Whalley GA

更新日期：2009-09-01 00:00:00

abstract：:Galectins are a family of soluble beta-galactoside-binding lectins that play many important regulatory roles in inflammation, immunity, and cancer. Recently, a role for galectin-3 in the pathophysiology of heart failure (HF) has been suggested. Numerous studies have demonstrated the up-regulation of galectin-3 in hype...

journal_title：European journal of heart failure

authors： de Boer RA,Voors AA,Muntendam P,van Gilst WH,van Veldhuisen DJ

更新日期：2009-09-01 00:00:00

abstract：:The use of Left Ventricular Assist Devices (LVADs) has increased over the last decade because of the lack of healthy donor hearts. In this report we describe for the first time a patient with an LVAD Heart Mate II (HM II) implanted 6 months before admission, who initially suffered from severe anaemia and later on unde...

journal_title：European journal of heart failure

authors： Gogas BD,Parissis JT,Filippatos GS,Iliodromitis EK,Soultanis KC,Kostopanagiotou GG,Theodoropoulos SP,Kremastinos DT,Yacoub MH

更新日期：2009-08-01 00:00:00

abstract：AIMS:Severe heart failure (HF) is often associated with cachexia that reverses post-heart transplantation (HTx) with frequent development of obesity. Ghrelin is a novel appetite-stimulating hormone. The aim was to determine the role of ghrelin in regulating appetite, food intake, and body composition in HF and post-HTx...

journal_title：European journal of heart failure

authors： Lund LH,Williams JJ,Freda P,LaManca JJ,LeJemtel TH,Mancini DM

更新日期：2009-08-01 00:00:00

abstract：:The use of erythropoietin (EPO) has revolutionized the treatment of anaemia associated with many conditions including chronic kidney disease (CKD). However, little is known of the cellular impact of EPO on the uraemic heart. The discovery that the EPO receptor (EPOR) is also expressed on non-haematopoietic cells inclu...

journal_title：European journal of heart failure

authors： Smith K,Semple D,Bhandari S,Seymour AM

更新日期：2009-08-01 00:00:00

abstract：AIMS:Previous evaluations of natriuretic peptide (NP) levels in patients with acute dyspnoea presenting to the emergency department (ED) have selected only a minority of patients for echocardiography. We aimed to evaluate the association between NPs and more subtle echocardiographic findings and to assess the potential...

journal_title：European journal of heart failure

authors： Shah KB,Kop WJ,Christenson RH,Diercks DB,Kuo D,Henderson S,Hanson K,Li SY,deFilippi CR

更新日期：2009-07-01 00:00:00

abstract：AIMS:We sought to test the utility of weight gain algorithms to predict episodes of worsening heart failure (WHF) using home-telemonitoring data collected as part of the TEN-HMS study. METHODS AND RESULTS:Simple rule-of-thumb (RoT) algorithms (i.e. 3 lbs in 1 day and 5 lbs in 3 days) and a moving average convergence d...

journal_title：European journal of heart failure

authors： Zhang J,Goode KM,Cuddihy PE,Cleland JG,TEN-HMS Investigators.

更新日期：2009-04-01 00:00:00

abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...

journal_title：European journal of heart failure

authors： Mele D,Toselli T,Capasso F,Stabile G,Piacenti M,Piepoli M,Giatti S,Klersy C,Sallusti L,Ferrari R

更新日期：2009-04-01 00:00:00

abstract：AIMS:Impaired tissue perfusion is often observed in patients with acute heart failure. We tested whether low-dose nitroglycerin (NTG) improves microcirculatory perfusion in patients admitted for acute heart failure. METHODS AND RESULTS:In 20 acute heart failure patients, NTG was given as intravenous infusion at a fixe...

journal_title：European journal of heart failure

authors： den Uil CA,Lagrand WK,Spronk PE,van der Ent M,Jewbali LS,Brugts JJ,Ince C,Simoons ML

更新日期：2009-04-01 00:00:00

abstract：AIMS:The Home or Hospital in Heart failure (HHH) study was a European Community-funded, multinational, randomized controlled clinical trial, conducted in the UK, Poland, and Italy, to assess the feasibility of a new system of home telemonitoring (HT). The HT system was used to monitor clinical and physiological paramet...

journal_title：European journal of heart failure

authors： Mortara A,Pinna GD,Johnson P,Maestri R,Capomolla S,La Rovere MT,Ponikowski P,Tavazzi L,Sleight P,HHH Investigators.

更新日期：2009-03-01 00:00:00

abstract：:Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics incurring significant morbidity and mortality. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. Evaluation of cardiac and pulmonary function is often problematic and occasionally...

journal_title：European journal of heart failure

authors： Hawkins NM,Petrie MC,Jhund PS,Chalmers GW,Dunn FG,McMurray JJ

更新日期：2009-02-01 00:00:00

abstract：AIMS:Supervised exercise can benefit selected patients with heart failure, however the effectiveness of home-based exercise remains uncertain. We aimed to assess the effectiveness of a home-based exercise programme in addition to specialist heart failure nurse care. METHODS AND RESULTS:This was a randomized controlled...

journal_title：European journal of heart failure

authors： Jolly K,Taylor RS,Lip GY,Davies M,Davis R,Mant J,Singh S,Greenfield S,Ingram J,Stubley J,Bryan S,Stevens A

更新日期：2009-02-01 00:00:00

abstract：AIMS:Randomized trials have shown that beta-blockers (BBs) reduce mortality in chronic heart failure (HF). Less data are available on the role of BBs in patients with acute HF, specifically if BBs should be continued or temporarily withdrawn. The aim of this study was to evaluate the role of BBs on in-hospital outcomes...

journal_title：European journal of heart failure

authors： Orso F,Baldasseroni S,Fabbri G,Gonzini L,Lucci D,D'Ambrosi C,Gobbi M,Lecchi G,Randazzo S,Masotti G,Tavazzi L,Maggioni AP,Italian Survey on Acute Heart Failure Investigators.

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Crataegus preparations have been used for centuries especially in Europe. To date, no proper data on their efficacy and safety as an add-on-treatment are available. Therefore a large morbidity/mortality trial was performed. AIM:To investigate the efficacy and safety of an add-on treatment with Crataegus ext...

journal_title：European journal of heart failure

authors： Holubarsch CJ,Colucci WS,Meinertz T,Gaus W,Tendera M,Survival and Prognosis: Investigation of Crataegus Extract WS 1442 in CHF (SPICE) trial study group.

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is frequent among patients hospitalized with acute heart failure syndromes (AHFS). AIMS:To describe the influence of coronary revascularization status on survival in patients with AHFS. METHODS AND RESULTS:OPTIMIZE-HF enrolled 48,612 patients with AHFS from 259 U.S. hospitals....

journal_title：European journal of heart failure

authors： Rossi JS,Flaherty JD,Fonarow GC,Nunez E,Gattis Stough W,Abraham WT,Albert NM,Greenberg BH,O'Connor CM,Yancy CW,Young JB,Davidson CJ,Gheorghiade M

更新日期：2008-12-01 00:00:00

abstract：:The incidence and prevalence of cardiovascular disease increases progressively with advancing age. Cardiovascular disease is a major cause of morbidity and mortality in Western Countries. In the near future, as the population ages, it is expected that the population prevalence of cardiovascular disease will increase d...

journal_title：European journal of heart failure

authors： Wong LS,de Boer RA,Samani NJ,van Veldhuisen DJ,van der Harst P

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:In patients with heart failure and reduced left ventricular ejection fraction, angiotensin receptor blockers have been found to reduce mortality and morbidity and to prevent or reverse left ventricular remodelling, compared to optimized background treatment. In light of these data, The Heart failure Endpoint...

journal_title：European journal of heart failure

authors： Konstam MA,Poole-Wilson PA,Dickstein K,Drexler H,Justice SJ,Komajda M,Malbecq W,Martinez FA,Neaton JD,Riegger GA,Guptha S

更新日期：2008-09-01 00:00:00

abstract：:Many patients with Congestive Heart Failure (CHF) are anaemic. This anaemia is associated with more severe CHF and a higher incidence of mortality, hospitalisation and morbidity. The only way to prove that the anaemia is causing this worsening of CHF is to correct it. We review here some of the published papers about ...

journal_title：European journal of heart failure

authors： Silverberg DS,Wexler D,Iaina A,Schwartz D

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, left ventricular ejection fraction (LVEF) and survival in patients with heart failure and wide QRS, however, long term clinical outcome is unknown. AIMS:To identify predictors of mortality and evaluate the effects of CRT after long term follow-up. ...

journal_title：European journal of heart failure

authors： Kronborg MB,Mortensen PT,Kirkfeldt RE,Nielsen JC

更新日期：2008-08-01 00:00:00

abstract：AIM:We used Near Infrared Spectrophotometry (NIRS) during arterial occlusion to measure resting skeletal muscle oxygen consumption in chronic heart failure (CHF) patients and in age-matched healthy volunteers (HVs). METHODS:Fifteen CHF patients (ten males) and eleven HVs (six males) had echocardiographic evaluation fo...

journal_title：European journal of heart failure

authors： Abozguia K,Phan TT,Shivu GN,Maher AR,Ahmed I,Wagenmakers A,Frenneaux MP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Approximately one third of patients with chronic heart failure have left bundle branch block (LBBB) on their 12-lead ECG. METHODS AND RESULTS:1418 consecutive patients (average (SD) age 70.5 (10.4) years; 74% male) first seen in a community heart failure clinic between December 2001 and June 2006 had a 12 l...

journal_title：European journal of heart failure

authors： Clark AL,Goode K,Cleland JG

更新日期：2008-07-01 00:00:00

abstract：AIMS:A restrictive transmitral filling (RF) pattern predicts increased mortality in heart failure (HF) with reduced left ventricular (LV) systolic function. We performed a combined evaluation of LV function and RF for prognosis in patients with HF with and without systolic dysfunction. METHODS AND RESULTS:Doppler echo...

journal_title：European journal of heart failure

authors： Akkan D,Kjaergaard J,Møller JE,Hassager C,Torp-Pedersen C,Køber L,EchoCardiography and Heart Outcome Study (ECHOS) investigators.

更新日期：2008-07-01 00:00:00

abstract：AIMS:This study was designed to assess whether the prognostic significance of estimated glomerular filtration rate (eGFR) and left ventricular ejection fraction (LVEF) interact in populations with heart failure (HF) and myocardial infarction (MI). METHODS:Patients were recruited from four screening registers (N=18,010...

journal_title：European journal of heart failure

authors： Schou M,Torp-Pedersen C,Gustafsson F,Abdulla J,Kober L

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Sleep disordered breathing (SDB), especially Cheyne-Stokes respiration (CSR) is common in patients with chronic heart failure (CHF). Adaptive servoventilation (ASV) was recently introduced to treat CSR in CHF. The aim of this study was to investigate the effects of ASV on CSR and CHF parameters. ME...

journal_title：European journal of heart failure

authors： Oldenburg O,Schmidt A,Lamp B,Bitter T,Muntean BG,Langer C,Horstkotte D

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The role of the right ventricle has been relatively neglected proportionate to its importance. We sought to evaluate the impact of right ventricular (RV) and NT-proBNP on the outcome of patients with heart failure (HF) and functional mitral regurgitation (MR). METHODS AND PATIENTS:Outpatients with left vent...

journal_title：European journal of heart failure

authors： Dini FL,Fontanive P,Panicucci E,Andreini D,Chella P,De Tommasi SM

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The adipocyte-specific cytokine adiponectin, has cardioprotective effects, correlates with endogenous cardiac natriuretic peptides and adipocyte has guanylyl cyclase-A receptors of natriuretic peptides. AIMS:To evaluate the effect of carperitide (atrial natriuretic peptide; ANP) on plasma adiponectin in pat...

journal_title：European journal of heart failure

authors： Tanaka T,Tsutamoto T,Sakai H,Nishiyama K,Fujii M,Yamamoto T,Horie M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:We describe the baseline characteristics of subjects randomised in the largest placebo-controlled, morbidity-mortality trial to date in patients with heart failure and preserved ejection fraction - the irbesartan in heart failure with preserved systolic function trial (I-PRESERVE). METHODS AND RESULTS:4133 ...

journal_title：European journal of heart failure

authors： McMurray JJ,Carson PE,Komajda M,McKelvie R,Zile MR,Ptaszynska A,Staiger C,Donovan JM,Massie BM

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Acute dyspnoea as a presenting symptom is a frequent diagnostic challenge for physicians. The main differential diagnosis is between dyspnoea of cardiac and non-cardiac origin. Natriuretic peptides have been shown to be useful in this setting. Ultrasound lung comets (ULCs) are a simple, echographic method wh...

journal_title：European journal of heart failure

authors： Gargani L,Frassi F,Soldati G,Tesorio P,Gheorghiade M,Picano E

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:High-sensitivity C-reactive protein (CRP) is an inflammatory marker that predicts coronary heart disease (CHD) and, in recent studies, incident heart failure (HF). Whether the association of inflammation with incident HF is explained by worse baseline left ventricular dysfunction or by underlying CHD is unkn...

journal_title：European journal of heart failure

authors： Williams ES,Shah SJ,Ali S,Na BY,Schiller NB,Whooley MA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:A low peak oxygen uptake (pVO(2)) and steep VE/VCO(2) slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to a more accurate predictor of prognosis than using either alone. METHOD...

journal_title：European journal of heart failure

authors： Ingle L,Witte KK,Cleland JG,Clark AL

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Recent advances in pharmacological and pacemaker-based treatments for heart failure (HF) have brought about significant improvements in left ventricular function. AIMS:To identify the proportion of treated systolic HF patients in whom left ventricular systolic function improves and/or returns to normal. ME...

journal_title：European journal of heart failure

authors： Murphy NF,O'Loughlin C,Ledwidge M,McCaffrey D,McDonald K

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Suppression of the renin-angiotensin-aldosterone system (RAAS) is therapeutically valuable in chronic heart failure (CHF). RAAS inhibition can be achieved in a number of ways though an orally active renin inhibitor (RI) has never been studied before. We describe the neurohumoral effects of an RI. METHODS AN...

journal_title：European journal of heart failure

authors： Seed A,Gardner R,McMurray J,Hillier C,Murdoch D,MacFadyen R,Bobillier A,Mann J,McDonagh T

更新日期：2007-11-01 00:00:00

abstract：AIM:To investigate the role of MMP-2 and MMP-9 in cardiac remodelling induced by tobacco smoke exposure in rats. METHODS:Rats were allocated into two groups: C (n=9): control animals; ETS (n=9): exposed to tobacco smoke. After 4months, the animals underwent echocardiography, morphometric study and determination of MMP...

journal_title：European journal of heart failure

authors： Castardeli E,Duarte DR,Minicucci MF,Azevedo PS,Matsubara BB,Matsubara LS,Campana AO,Paiva SA,Zornoff LA

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Ultrastructural findings of idiopathic dilated cardiomyopathy (IDCM) include myocyte atrophy and myofilament loss, yet little is known about the vascular abnormalities present in IDCM. METHODS AND RESULTS:Patients with IDCM and controls underwent multi-slice CT to examine length and diameter of epicardial v...

journal_title：European journal of heart failure

authors： Roura S,Planas F,Prat-Vidal C,Leta R,Soler-Botija C,Carreras F,Llach A,Hove-Madsen L,Pons Lladó G,Farré J,Cinca J,Bayes-Genis A

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Heart failure is common in diabetes and ischaemic heart disease is the most likely link. Still, it has been suggested that the relation extends beyond such disease. METHODS:7060 subjects with two or more visits in the Reykjavík Study were followed--during 30 years from 1967. All underwent oral glucose toler...

journal_title：European journal of heart failure

authors： Thrainsdottir IS,Aspelund T,Gudnason V,Malmberg K,Sigurdsson G,Thorgeirsson G,Hardarson T,Rydén L

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Although heart failure (HF) is a common cardiovascular disorder, to date little research has been conducted into possible associations between HF and structural abnormalities of the brain. AIMS:To determine the frequency and pattern of magnetic resonance imaging (MRI) abnormalities in outpatients with chron...

journal_title：European journal of heart failure

authors： Vogels RL,van der Flier WM,van Harten B,Gouw AA,Scheltens P,Schroeder-Tanka JM,Weinstein HC

更新日期：2007-10-01 00:00:00